GLP-1 Cost Comparison

Compare what you'll actually pay for Ozempic, Wegovy, Mounjaro, and Zepbound based on your insurance status. Prices updated for 2026.

Your insurance coverage

Compare medications

Wegovy

Semaglutide · Novo Nordisk · Weight Management

List price

$1,349/mo

NovoCare Intro (0.25-0.5 mg, first 2 fills)

Through 6/30/2026 for new patients

$199/mo

NovoCare Self-Pay (all injection doses)

Direct from NovoCare Pharmacy

$349/mo

Wegovy Oral (1.5-4 mg tablet)

New oral formulation, launched early 2026

$149-$199/mo

Wegovy Oral (9-25 mg tablet)

Higher oral doses

$299/mo

Zepbound

Tirzepatide · Eli Lilly · Weight Management

List price

$1,086/mo

LillyDirect Vial (2.5 mg)

Single-dose vial, home delivery or Walmart pickup

$299/mo

LillyDirect Vial (5 mg)

Single-dose vial

$399/mo

LillyDirect Vial (7.5-15 mg)

Must refill within 45 days to maintain price

$449/mo

Savings Card (self-pay pens)

Prefilled pen for eligible self-pay patients

$499/mo

Key cost factors

Insurance is the biggest variable

With a savings card + commercial insurance, you may pay as little as $25/month. Without coverage, expect $199-$550/month through manufacturer programs.

Weight loss coverage is declining

Only ~19% of employer plans cover GLP-1s for weight loss. Coverage for Wegovy dropped 42% and Zepbound 12% in 2026 vs. 2025. Diabetes indications have much better coverage.

Vials vs pens

Zepbound vials via LillyDirect ($299-$449) are significantly cheaper than prefilled pens ($1,086 list). Requires drawing up with a syringe but saves hundreds per month.

Compounding status

The FDA resolved both semaglutide and tirzepatide shortages in 2025. Standard compounding of these medications is no longer permitted, making manufacturer programs the primary self-pay option.

Pricing disclaimer: All prices are estimates based on publicly available manufacturer programs, pharmacy pricing, and insurance data as of early 2026. Actual costs may vary based on pharmacy, location, insurance plan specifics, and eligibility for savings programs. Verify pricing with your pharmacy and insurance provider before making treatment decisions.

A vetted provider can help navigate costs

Good providers know which savings programs you qualify for, which pharmacies have the best pricing, and whether a brand-name or alternative makes more sense for your budget.

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