BPC-157
Also known as: Body Protection Compound-157
A synthetic peptide derived from human gastric juice, studied primarily in animal models for its regenerative and anti-inflammatory properties. Not FDA-approved.
How it works
BPC-157 appears to modulate the nitric oxide system, upregulate growth factor expression (VEGF, EGF), and promote angiogenesis. It has shown protective effects on the GI tract and accelerated healing in connective tissues in animal studies.
Common uses
- Tendon and ligament injury support
- Gut healing and inflammation
- Joint pain and recovery
- Muscle injury repair
Side effects
- Limited human safety data available
- Anecdotal reports of mild nausea
- Injection site irritation
- Unknown long-term effects
Key research
- Multiple rodent studies on Achilles tendon and MCL healing
- Animal models showing gastroprotective effects against NSAIDs
- In-vitro studies on fibroblast migration and tendon cell outgrowth
Safety notes
- No completed human clinical trials
- Added to FDA list of substances that cannot be compounded (2023-2024)
- Quality and purity vary significantly between suppliers
- Should only be considered under direct medical supervision
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